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Regenerative Medicine

Stem Cell Therapy at Grey Bruce Pet Hospital

Since 2003, Stem Cells have been utilized by small and large animal Veterinarians for the treatment of orthopedic cases world wide. Traditional services provided a mail in program whereas cells could be processed and sent back to the practitioner for reintroduction to the patient. Since then, innovation and improvements to various segments have driven a more wide commercial appeal for the service. With improved on-site technology the Grey Bruce Pet Hospital utilizes an in-clinic system which allows for a same day harvest and application to the patient. This eliminates the variability in outside shipping of the sample, dramatically reduces the costs of the treatment and allows for the best in viability eliminating the potential of cell death. Stem cells are the body’s repair cells. They have the potential to divide and differentiate into many different types of cells. Stem cells have the ability to differentiate into tissues such as skin, fat, muscle, bone, cartilage, and nerve to name a few.

What are the Types of Stem Cells?

There are two basic types of stem cells; embryonic and somatic (adult). Embryonic stem cells are found in the embryo. These cells are called totipotent or pluripotent, which means they have the ability to reproduce into any mature cell type. While embryonic stem cells were thought to offer the greatest potential in differentiating into any mature cell type, there are obviously moral and ethical concerns with harvesting these cells. They also have a propensity to develop into teratomas, a type of tumor, which is a major safety concern. The second type of stem cell is the adult stem cell. These stem cells are multipotent, which means they can still differentiate into multiple different tissues, but unlike embryonic stem cells, they do not develop into teratomas. Due to this, adult stem cells have a major safety advantage over embryonic stem cells. Adult stem cells are found in organs and tissues, such as bone marrow, adipose tissue (fat), skin, liver, blood vessels, and neurons. There are no moral or ethical concerns with harvesting adult stem cells from a patient, activating them, and reintroducing them back into the patient.

Why Does Grey Bruce Pet Hospital Use Adipose Tissue?

Adult stem cells are highly concentrated in adipose tissue (fat). Fat is also readily available in large quantities and easily accessible. The technique to acquire the stem cell is less invasive and less painful than aspirating a bone marrow sample from the hip or the sternum. There are up to 1,000 times more stem cells in a gram of fat than in a gram of bone marrow. At this concentration and with MediVet’s patented technology, the procedure provides an abundance of stem cells to treat in-clinic, same day without the need and additional expense of an outside culturing facility. The extraction is less invasive than a spay and very easy to obtain. Stem cells are extracted from the fat among a mixture of cells termed the Stromal Vascular Fraction (SVF). The SVF is rich in complementary cells and bioactive peptides that contribute to cell proliferation and tissue regeneration, and also imparts anti-inflammatory effects.